Biocompatible nanoadhesive offers hope for safer corneal transplants, reducing inflammation and infection risks

A research team from the Eye & ENT Hospital of Fudan University, China, has developed a novel biocompatible nanoadhesive for corneal transplantation. The nanoadhesive is based on tetrahedral framework nucleic acids combined with functionalized polycationic recombinant proteins. This unique composition minimizes the risks of tissue necrosis and inflammation associated with polymeric adhesives while inhibiting bacterial growth and promoting tissue repair. This work demonstrates an efficient strategy to break through the bottleneck of current ophthalmic adhesives.