Cross-species transplantation: Generation of rat offspring from ovarian oocytes in mice

The idea of maturing oocytes in the ovary to produce offspring has been implemented in various ways. One such method, ovarian transplantation, is a relatively simple procedure for obtaining eggs, compared to in vitro culture of ovaries and follicles. However, it is still difficult to transplant ovaries into cellular immunodeficient mice and produce offspring from the eggs grown in the mice.