Fluidizing the cell membrane: Effective internalization of lipid nanoparticles for photodynamic cancer therapy

In order to deliver cancer therapeutics to tumor cells, the cells' membranes must be overcome. A team of researchers have discovered a simple way to achieve this using lipid nanoparticles containing the reagent EDTA (ethylenediaminetetraacetic acid). As the team report in the journal Angewandte Chemie, an unusual mechanism of action of EDTA is responsible for this useful effect.