How directional connections shape complex dynamics in neuronal networks

Uncovering the relationship between structure (connectivity) and function (neuronal activity) is a fundamental question across many areas of biology. However, investigating this directly in animal brains is challenging because of the immense complexity of their neural connections and the invasive surgeries that are typically needed. Lab-grown neurons with artificially controlled connections may become a useful alternative to animal testing, particularly as we learn how to accurately characterize their behavior.