Importance of RNA modifications in fungal infection resistance could lead to better treatments

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a German-Austrian research team led by the Leibniz Institute for Natural Product Research and Infection Biology–Hans Knöll Institute (Leibniz-HKI). Their study, published in Nucleic Acids Research, focused on the mold fungus Aspergillus fumigatus, which can cause life-threatening infections, especially in immunocompromised people.