Optimizing the Tet-On system for homogeneous iPSC myogenic differentiation

In a recent study published in iScience, researchers have optimized the Tet-On system to improve the efficiency of generating skeletal muscle cells and other differentiated cell types from iPSCs for various basic and clinical research purposes. The team was led by Associate Professor Hidetoshi Sakurai (Department of Clinical Application) and Associate Professor Knut Woltjen (Department of Life Science Frontiers).