Solid-phase reversible immobilization beads for rDNA high-throughput sequencing library construction

Solid-phase reversible immobilization (SPRI) beads are widely used for high-throughput sequencing library construction to purify and recover nucleic acids. A new study published in Zoonoses has investigated the effects of SPRI bead ratio, incubation time, and elution time on nucleic acid recovery during full-length 16S rDNA high-throughput sequencing library construction.