The role of interfacial amino acids in shaping bio-electronic communication between proteins

Proteins are vital for facilitating charge transport (CT) chain reactions, both within individual proteins and between proteins. Understanding CT in proteins is crucial for biological processes and the development of bioelectronic devices. While previous research has focused on CT within proteins, less attention has been given to inter-protein CT. Recent studies suggest that specific interactions between proteins are stabilized by interfacial amino acids, potentially mediating CT between proteins.