Unveiling biosynthesis of hyperoside: A pathway to sustainable production in Hypericum monogynum

Hyperoside, a beneficial flavonoid galactoside found in both medicinal and edible plants, plays a critical role in plant growth, self-defense, and breeding, as well as in human health through its numerous pharmacological properties. However, the biosynthetic pathway of hyperoside in plants, including its original source, Hypericaceae, has not been systematically elucidated yet.